The larger the gap and the spark, the better ignition of the fuel/air mixture,
BUT, the higher the pressure of the various gaseous components in the gap, the harder it is for the spark to jump. Pressure in the gap is higher with high compression heads, and, with any head when you open the throttle, which is why you would decrease the gap with HC heads (all else being equal), and why marginal ignition systems produce misfiring and backfiring "under load." ALSO, longer sparks are more easily blown out by turbulence. Normally, lots of turbulence in the combustion chamber is a good thing (for preventing hot spots), but then a stronger ignition system is needed to sustain the spark.