I've been into FE's heavily most of my life. Currently have 3 of them, all in running vehicles, including a 427 MR in my '69 Mach 1.
All 427's have the same bore and stroke (originally), or they would not be 427 cubic inches. All 427 blocks are NOT the same. Early ones have 2 bolt mounts and round cylinders. Later ones use 4 bolt mounts and have clover leave cylinders that improved cylinder rigidity. There are other differences.
A LOT of marine 427's were made. Usually non-sideoilers, although they can and often do have the "hump" down the side of the block, they just aren't drilled. Many of them are reverse rotation, so you have to look out for cranks used in them as the oil slots on the back seal area will push oil OUT of the engine if tried to use in a standard rotation.
SOHC's are not specially machined on the front. The front plate and cover takes care of all the sealing. They DO have an extra drain hole for the oil in the head, towards the lower back part of the deck. They are VERY scarce these days. Usually guys will just run external oil returns to get around that.
There are other differences between older and later blocks. They were racing engines, and Ford improved them as they realized their shortcomings for LeMans and Nascar.