I was thinking about the Edelbrock 500 some more. I've never run a 4 bbl so I don't know, but I would think it was be right on par with running a 3X2 set-up.
If I recall correctly, three 97's wide open would get you in the ballpark of 450 cfm. The beauty of the 4 bbl. is that it only gives you full cfm when your foot is in it. Others, you are only running on the primaries.