Keep in mind there were two types of distributors used on 8BA family engines in the time frame of 1948 through 1953. The old 7RA type distributor 1948/50 Ford car/truck will not fit in an OCM type (1950 & later Merc) aluminum front cover and visa versa. After 1951 or so they were generally using the OCM types but I don't know about Ford trucks.
Another difference is the type of carburetor since the Holley Load-O-Matic spark advance was controlled by the carb. I think that the advance curve was pretty much the same though so it doesn't make all that much difference.
If a person changes distributors, they have to consider the type of front cam chest cover.