The anti-freeze protection doesn't wear out, fwiw, if that is a primary concern. The anti-corrosion additives do get used up.
Ethylene Glycol is interesting stuff, a safe bar bet to win - pure EG will freeze at about +10° F. it absolutely requires the addition and mixing with water to get extended freeze protection. 50/50 will get protection to -34° F., and for the real cold, a 70/30 mix of glycol and water is good to ... I dunno, but I'm staying inside with a cup of hot cocoa! The heck with that!