4, 6, or 8 cylinders makes no difference on a coil or even condensor for that matter. A typical V8 from later years like a SBC, or a mallory distributor, SBF etc operate on around 28 degrees of dwell and the 00012 coil would have too much resistance to provide a hot spark. On the 32-48 Fords however the run on 36 degrees of dwell and have a longer coil charge time and require less amperage to create a hot spark. The total primary resistance on a Early Ford 6v from the factory is 1.6 ohms. When you double the voltage and go to 12V you need to double the resistance (so 3.2 ohms or close to it). Any much more and you'll have a weak spark. Too much less and the points will pit and burn up prematurely.
This is what makes the Bosch coil ideal. It is the correct resistance, and in the 00012 case it is epoxy filled so it can be mounted in any position and is better suited for heat.