I'm running a 2GC on my '51 Ford with a '51 Merc engine. I have an aluminum Canadian Mercury manifold that I have bored out all the way down to the 2G throttle bore size. If you mount the carburetor backwards, the fuel and throttle hookups almost fall into place by themselves. A manual choke is a problem because it wants to pull the wrong way. I solved this by utilizing an automatic choke. The Mercury's originally came with an automatic choke, so there are provisions for one. The 2GC has an integral choke and the Mercury heat tube hooked right up to it after shortening it a bit. It has been in the upper 30's low 40's here in Minnesota this spring and the car starts easily. One pump to set the choke, hit the switch and it's running. I am extremely happy with the way the car runs and performs. As said before, you should not use the stock distributor with this setup, so I have installed a Mallory dual point. With this setup, along with a set of "massaged" Edmunds heads, I can easily keep up with traffic.
I liked this setup so well, I decided to make another one using the cast iron manifold from the '51 Mercury engine. I also bored this out all the way down (a task that was easier than I had anticipated) and mounted the carburetor backwards. The '51 Mercury used a "divorced" choke (the choke mechanism is mounted on the manifold rather the the carburetor), so on this one, I used a 2GV that is designed for this kind of operation. Again, the linkage almost fell into place, with just a slight bending of the choke rod necessary to make it work. I had this mounted on my "Hot Rod" engine on my test stand for initial start up, and it also performed flawlessly.
As to which carburetor to use, you should be aware that the vast majority of 2G's out there are what are referred to as "large base" and will not fit on the Mercury manifold without an adapter (which defeats the whole purpose). What you need is a "small base" version that came on late '50's Chevrolets and a few other vehicles. These are becoming quite hard to find and the price of cores is climbing. They come in three varieties, those with manual chokes (2G's), those with integral chokes (2GC's), and those with the divorced chokes (2GV's). Ideally, you would want to match the carburetor type to the Mercury manifold, but as I said before, small base carbs are hard enough to find without trying to zero in on a specific type.
If you want. I can post pictures of both setups later.