Jag rear end/suspension use to be the hot rodders hot ticket, but of course you will notice it from behind. S-10 can be made to work, but most of the newer rears are going to be an open driveline. Since later brakes bolt onto the A rear, that is your easiest and probably cheapest route. Later Ford banjo has the hangers behind the axle, and the wrong length driveshaft, so no, not a boltin. You will also run into wheel bolt pattern issues with most swaps.
Unless you re like me and just like to go against the flow, probably not good to change out the rear. If yours is shot, you can rebuild it, or there are a jillion of them out there for CAMO prices. (CAMO- cheap a__ model A Owner)
(Well, there ain't nuthin' cheap when it comes to restoring old iron except the person doing it.)