You'll use the main bearings for a 59A and whatever rod bearings match the rods you're using.
If you have them, I'd go ahead and run the later 49-53 rods with the insert bearings. If you don't have these rods, I'd find a set and have them rebuilt.
There is no great reason to run 59A full-floater bearings and rods unless you have already purchased/own them and the rods/bearings have been correctly setup. There are very few machine shops that know how to setup full-floater bearings these days.