The six spline half of a 10x6 spline coupler/adaptor can also be used to replace the ten spline bung end of an early tubular driveshaft, if you are putting a six spline R&P set in an early rear, and do not want to use a solid driveshaft with center bearing torque tube, this might be the best way to go.
Some of those 10x6 spline couplers/adaptors are larger in diameter than the original Ford 6x6 spline coupler/adaptor. I don't believe that larger diameter would cause any problems regardless of how you plan to use it. JMO