Well, you said you had the parts . . . so I don't see a cost issue.
A 276 is a 4" stroke crank with a 3 5/16 bore. A 284 is a 4 1/8" stroke crank with a 3 5/16 bore . . . so the bore is the same on both.
If you already have a 4 1/8" stroke crank and the correct rods, might as well go to 284. Where the complexity/cost can come into play is if you don't have the correct rods/bearings for the smaller journals and also need to offset grind a 4" Merc crank to a small-journal 4 1/8" stroke setup.
You can build a 276" engine with a basic 4" stroke 49-53 Merc crank and use the late 49-53 rods. You'll not need to go the "traditional" 91A/21A rods with full-floating bearings or aftermarket H-beam rods . . . and you won't have to offset grind the crank. A rough guess is that this will save you about $1000.
Now, if you buy an aftermarket 4 1/8" stroker crank and it is setup for the larger journals (49-53 rods), then this is not a bad way to go either (except the cost of the crank and the balancing required). Bearings are super cheap (insert bearings) and you'll not have to fuss with full-floater rod bearing setup/sizing. Most "modern" machine shops have never setup/ran full-floater bearings . . . they have no clue as to what they're all about.
Lots of ways to skin the flathead cat! It usually comes down to time and money . . .
B&S