Optimum gear ratio is a matter of driving style, geography, traffic etc. If you go to the gear ratio calculator and enter your correct tire size, 2500rpm, 70 mph, use 5% default on converter slippage, it says you’re looking for a 2.83:1 rear gear. That’s pretty tall, and taller than any of the options.
If your merco starts in second like a fordo, it’s really going to be slow leaving stop. In Seattle with the hills, it would be a disaster, you’d be manually selecting low all the time. Same problem on the freeways, we’ve got lots of long grades and that ratio would put you downshifting to 2nd. And worse in our usual bumper to bumper traffic.
Kansas, I don’t know. If you leave the driveway on the levels and go 50 miles before you slow down, might work.
The other concern is the availability of parts for a 45. My bird had a 44 out of a truck, but even so, it’s not cheap to work on, and since the “pumpkin” doesn’t come out, it’s all under the car.
Assuming the engine is in good condition, your not going to hurt it driving at 3000rpm. Truck y blocks did a lot of that. Bit noisy, but it mostly disconcerting because we’re no longer used to it.