Depending on what's in the engine, stock or modified. I like to have the mechanical advance go to 20 degs BTDC at @2000RPN. This is a good starting point. Next set the vacuum advance to 8 degrees, for cruise. Again this is just a starting point.
Those of you using the original pre 49 distributors will have to live with the built in advance and tere's not much you can do about it. You can however grind the advance slots but you can't change the springe pressure on the weights. The trick is to get the vacuum plunger set right??? I plan to putz with this when I have time.