Cam selection is a bit of a compromise; the efficiency of performance cams tends to push the RPM's of the engine up, with a corresponding lose of performance [from stock] in the lower rev ranges. I tend to cam and engine depending on it's ultimate use; if you are going to do the majority of your driving at, say, 60 MPH, you want a cam that is most efficient at those particular revs, say, for example, at that 60 MPH speed the engine is turning 2200 RPM, what is the point of running a cam that comes on at 4500RPM?
I think many owners tend to 'overcam' their engines, for any number of reasons. The whole picture needs to be carefully looked at; ultimate use, engine mods, rear axle gearing, weight of vehicle, transmission ratios etc....
All that said, I like the Isky 88 grind, in my particular application I want a cam that cruises comfortably at 70 MPH, with the power in reserve to perform overtaking maneuvers etc. The downside is that it can tend to be a bit 'jerky' trying to drive at 20 MPH in top gear, as opposed to the silky smoothness of a stock engine in the same application....but the stocker has run outta breath at 60! at's all a trade off.