The primary deciding factor in tube type vs.tubeless is the type of rubber compound that is used in the manufacture for the inner layer of rubber, known as the liner. Not to be confused with the flap, which a separate piece of the assembly used to prevent the rim chaffing the belly of the tube.
The tubeless designed tire uses a non-migratory rubber compound that will contain the air molecules, where as a true tube type tire's liner material is porous, in order to allow any air between the tube and liner to vent out.
The main benefit to running tubeless is that the tubeless liner will actually seal around a small penetration (nail), where with the tube being the air container, the smallest pentration will result in an instant flat.
The secondary benefit is that the tubeless tire runs a lot cooler than the tube type tire. The heat is generated by the constant flex movement of the liner against the tube, or vice versa. Heat buildup contributes to tube failure, casing separation and faster wear rate.
If you elect to run tubes, use a radial designated tube, regardless of the tire's construction. It should have heavier gauge rubber, stronger splices, and a reinforced, heavier based stem.